Clocks and Other Models#

Biolearn supports a number of clock models that can be easily run from the clock gallery. IP and usage information is provided here.

Name

Year

Species

Tissue

Predicts

Source

Coefficients

Horvathv1

2013

Human

Multi-tissue

Age (Years)

paper

coefficients file

Hannum

2013

Human

Blood

Age (Years)

paper

coefficients file

Lin

2016

Human

Blood

Age (Years)

paper

coefficients file

PhenoAge

2018

Human

Blood

Age (Years)

paper

coefficients file

YingCausAge

2022

Human

Blood

Age (Years)

paper

coefficients file

YingDamAge

2022

Human

Blood

Age (Years)

paper

coefficients file

YingAdaptAge

2022

Human

Blood

Age (Years)

paper

coefficients file

Horvathv2

2018

Human

Skin + blood

Age (Years)

paper

coefficients file

PEDBE

2019

Human

Buccal

Age (Years)

paper

coefficients file

Zhang_10

2019

Human

Blood

Mortality Risk

paper

coefficients file

DunedinPoAm38

2020

Human

Blood

Aging Rate (Years/Year)

paper

coefficients file

DunedinPACE

2022

Human

Blood

Aging Rate (Years/Year)

paper

coefficients file

GrimAgeV1

2019

Human

Blood

Mortality Adjusted Age (Years)

paper

coefficients file

GrimAgeV2

2022

Human

Blood

Mortality Adjusted Age (Years)

paper

coefficients file

AlcoholMcCartney

2018

Human

Blood

Alcohol Consumption

paper

coefficients file

DNAmTL

2019

Human

Blood, Adipose

Telomere Length

paper

coefficients file

HRSInCHPhenoAge

2022

Human

Blood

Age (Years)

paper

coefficients file

Knight

2016

Human

Cord Blood

Gestational Age

paper

coefficients file

LeeControl

2019

Human

Placenta

Gestational Age

paper

coefficients file

SexEstimation

2021

Human

Blood

Sex

paper

coefficients file

LeeRefinedRobust

2019

Human

Placenta

Gestational Age

paper

coefficients file

LeeRobust

2019

Human

Placenta

Gestational Age

paper

coefficients file

SmokingMcCartney

2018

Human

Blood

Smoking Status

paper

coefficients file

DownSyndrome

2021

Human

Blood

Down Syndrome Prediction

paper

coefficients file

DeconvoluteBlood450K

2024

Human

Blood

Cell Proportions

paper

coefficients file

DeconvoluteBloodEPIC

2024

Human

Blood

Cell Proportions

paper

coefficients file

TwelveCellDeconvoluteBloodEPIC

2024

Human

Blood

Cell Proportions

paper

coefficients file

BMI_McCartney

2018

Human

Blood

BMI

paper

coefficients file

EducationMcCartney

2018

Human

Blood

Educational Attainment

paper

coefficients file

TotalCholesterolMcCartney

2018

Human

Blood

Total Cholesterol

paper

coefficients file

HDLCholesterolMcCartney

2018

Human

Blood

HDL Cholesterol

paper

coefficients file

LDLCholesterolMcCartney

2018

Human

Blood

LDL with Remnant Cholesterol

paper

coefficients file

BodyFatMcCartney

2018

Human

Blood

Percentage Body Fat

paper

coefficients file

BMI_Reed

2020

Human

Blood

BMI

paper

coefficients file

ProstateCancerKirby

2017

Human

Prostate

Prostate Cancer Status

paper

coefficients file

HepatoXu

2017

Human

Circulating DNA

Hepatocellular Carcinoma Status

paper

coefficients file

CVD_Westerman

2020

Human

Blood

Coronary Heart Disease Status

paper

coefficients file

AD_Bahado-Singh

2021

Human

Blood

Alzheimer’s Disease Status

paper

coefficients file

DepressionBarbu

2021

Human

Blood

Depression Risk

paper

coefficients file

TranscriptomicPredictionModel

2015

Human

Blood

Age (Years)

paper

coefficients file